👉 Link post to my article on Benchling's engineering blog. ☜

I wrote the article during my internship this summer with Benchling's Modified Biologics and Chemistry team. Check it out for a visual and interactive explanation of monomers, nucleotide structures, chemical image renderings, and rotation trigonometry!

Row of 21 circles representing nucleotides in a modified RNA sequence. Thee circle labeled “U” has a large tooltip underneath with the text “Sugar 2-O-Methylribose”, “Base Uracil”, and “3' Phosphate Phosphate”. The tooltip also contains an image of the chemical structure of the modified nucleotide.
Passenger strand of patisiran (the first siRNA drug that got FDA approval!) with a tooltip showing the chemical structure of one of the modified nucleotides.